There's an argument for Orb of the Deep Sea. Not universally BIS in all situations, but if you're doing something where there's no real risk of dying and/or you're not being CHed (say, an easy grind session with a non-cleric healer), maximum AC is the most efficient thing you can have. The FT from CT brain is nice if you don't have an enchanter or bard in the group, but if you do, it's pretty negligible. There are situations and group setups where 45 AC is better.
You can also get the orb for low dkp while the brain will cost you a year's worth.
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