Weird GFX glitch started happening a couple months ago randomly

[LongTallMatt]

I can reboot to clear it (I believe I can just restart the program, but like to make sure I clear gremlins). All software and drivers are up to date, self built, free of dust, not overheating in any way (that I can tell). Does anyone know what this might be? I play windows on a dual monitor system.

This is a screen cap of a portion of the game window when it bugs out:
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