You basically want as close to 200 as you can get for any given resist. For example, 182 unbuffed MR keeps me unfeared for pretty much all encounters. If it sticks, it breaks quickly.
MR The dragon killer. Absolutely get this as high as you can. 200 as an unrealistic, but ideal goal.
PR Trakanon's element. If you're FE / TMO, max this one too.
CR might be valuable for exping if you're a tank / puller / VP trainer, otherwise useless.
FR CAN help, but you have to drop MR to raise FR usually. Resisting a fear is way more important than reducing / resisting a fire AE.
DR is essentially useless for everyone, with one exception.
If you don't raid, disregard all of this and max your hp / str / mana / we.
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