Realistically, game-changers for a wiz are 1) jboots and 2) enough int/mp gear that you can quad. Consumables also make a world of difference though... stuff like leatherfoot raider skullcaps for getting out of jail free, shaman cure/heal pots (no more dying to a single necro/shaman dot when solo or something!), wooly spider silk nets for instant roots, etc.
Beyond that the only things that are really "game changers" are prohibitively expensive and/or difficult to obtain, like manastone, mana robe, fungus staff, wiz epic, wiz clicky VP robe, etc.
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