I've seen this a few times. The first time I messed up the pull of Drusella Sathir and had to hat out. I come back and she was gone along with the mob that was my pet. And yes, she had a NoS.
I'm not sure if DoT tics can do it, but any spell can for sure. Imagine this: Charmed Pet is fighting Caster A. Caster A begins to cast, you zone, breaking charm, mobs stop fighting, Caster A's spell keeps casting tho, lands on your former pet and now the pet is agro on Caster A. At this point other mobs can join in the fight, based on some really messed up assist mechanics. I've seen mobs fighting like this if I zoned out and came right back in, etc. It is rare, but an unfortunate risk when charming is involved.
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