Sounds like a lot of fun, I'm jealous and wish I could be a part of it. You could go to Permafrost much earlier than 45, mobs start out at level 15. Splitpaw (level 26+), Runnyeye (7-30+), Qeynos Aqueducts (1-15), Highpass Hold (12-22), Highpass Keep (18-35), Kerra Island (15-35), Kedge Keep (35-50), Upper Guk (4-25).
As far as what others are saying about needing certain classes, they may be right. But rule #1 in my book is play what you enjoy. I don't know the end game well enough to say you need this class or that class, but levels 1-50 you will be just fine.
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