Level up then if you want to remove a level 49 spell in two casts, with counteract disease. In your mid 50's you will be a plauge cureing fool, look out evil shaman.
But no, you should not wipe out a level 49 disease with a level 1 spell (for shaman) in two casts.
edit: and when was it boosted to remove four counters? Had to have been sometime after Planes of Power. not classic.
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