It could be the posion/disease icon is removed, but it still is ticking due to the strength.
Spells like those have Disease/Posion counters.
Take Insidious Fever:
Increase Disease Counter by 4
Decrease Disease Resist by 18 (L17) to 35 (L50)
Now look at Cure Disease:
Decrease Disease Counter by 1 (L1) to 4 (L12)
So a possibilty is that the icon is removed on the first cast, but it actually is still on the player. Have you tried to cast Cure Disease multiple times?
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