The formula to compare efficiency is (weapondmg x2 +dmgbonus)/delay. When in doubt math it out, there's a bunch of oddities out there so general rules might not apply to your situation.
Generally, speed kills but let's take a <28 monk for example
Adamantite club is 15/25 so (15x2+0)/25= 1.2
Jade mace is 9/18 so (9x2+0)/18=1
Slower club is better than fast mace, this remains true at 60. That's one of the few exceptions though because the club's ratio is among the best for droppable weapons. A 30/40 blam stick beats those two despite much slower delay.
Like crede said, once damage caps are lifted 2handers are often best value for the money if your class has access to them. Herbalist's spade will be close to sboz+boc combo while the former is like 6k and the latter combo 70k. A reaver is 5k and a peacebringer is 1k. You can easily swing those all the way to 60.
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