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Old 12-14-2025, 05:21 PM
Jimjam Jimjam is offline
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Join Date: Jul 2013
Posts: 12,769
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searching her name at scholar.google.com and filtering the pages to recent years produces lots of interesting stuff, much of it requires no subscriptions to view.


e.g. Antipsychotic dose reduction and discontinuation versus maintenance treatment in people with schizophrenia and other recurrent psychotic disorders in England (the RADAR trial): an open, parallel-group, randomised controlled trial

https://www.thelancet.com/journals/l...258-4/fulltext

A summarized summary:
Maintenance antipsychotic medication is recommended for people with schizophrenic diagnoses, but with adverse effects, and little evidence on long-term outcomes.

The study compared a gradual antipsychotic reduction with maintenance treatment for harms and benefits. The hypothesis was that antipsychotic reduction would improve social functioning with a short-term increase in relapse. At 2-year follow-up, a gradual, supported process of antipsychotic dose reduction had no effect on social functioning.

The authors hope their data can inform decisions regardling long term antipsychotic medication.
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