These are what I would say are objectively the best duos:
1. Enchanter - Cleric - Might struggle a little early on when enchanter's charms aren't very good and you might have to depend on their weak summoned pet, but this is objectively the most powerful duo in the game and doesn't require a lot of gear to be good. However, enchanters require the player to be on point and alert in an intense kind of way that I didn't particularly enjoy.
2. Monk - Shaman - More straightforward gameplay and less intense than Enchanter - Cleric, but still very capable and fun. Endgame would require a lot of time investment to get gear + spells for max capability.
3. Mage - Necro - really capable duo that can do endgame content (especially dungeon crawls and, requires zero gear to be good (I knew a Necro that purposely didn't have a single equipment item until level 60 and mage is the same way).
Honorable mentions:
Enchanter - Paladin
Magician - Shaman
Necro - Shaman
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