The best argument for JBB is it being 1/5th the price of an epic and resellable so from 45-60 it's a tolerable way to grind.
Once you get torp mana is less limited. JBB becomes a green killer like for someone whos painfully slogging through droga or adding to quick kills with a duo/trio after slowing. One click of Bane is a massive chunk of hps for the same cast speed...it's the workhorse of your spells and for most stuff the only damage spell you need on the bar.
The more hps something has the more a double-line debuff and disease makes sense. Hell start meleeing with your scourge mallet too I guess. Just not low hp stuff like in Chardok. On non-rooted stuff where you can sit/swap spells if you are quick, keeping disease on the bar takes up 3 gems. It's also half the kill speed of bane only once fully debuffed.
I guess if I was moving through greens I might pull with it, root, and epic click the epic. That gives the most dot/mana for the least amount of clicks. Overall though it's pretty underwhelming unless killing things in that 25k+ hp range, speculatively as I never have done that.
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