I suspect the frozen shard from killing shardwing courier quest is one of the best weapons. I think you can probably snare poison bow kite it even with terrible gear as long as you are moderately lucky with the snare resists.
You are going to want to camp a lot of
https://wiki.project1999.com/Serpent_Blood_Potion, as it effectively lets you carry up to 40000 HP with 8 full 10 slot bags. That vastly extends what you can kill. That, poison kiting with snare and blind and NPC vs npc fighting would be the mechanics I would be looking at to try for solo stuff.
For example, bracer of benevolence is likely possible, but challenging, because the Giants will fight the cov aligned stuff in zone. Your technique would be to train the giants and just the right amount of stuff to the DN entrance; after you zone, they fight. If you chose well and the sides are balanced, one side will barely win. You support the losing side with the sacks of serpent blood potions to keep you alive, then kill the captain from low life with serpent blood to give you enough HP to solo his last few percent.