I think Cleric and Enchanter are the two where you really cannot replace them. Sure you can use other classes at lower levels that would be more efficient, but when it comes down to 50+, where the real grind begins, you are gonna want that CH and the rez. So I would say 1-49 is debatable but 50+ there is no debate really. As for that third spot, Gotta go with a monk for pulls/splits. Gonna make life a lot easier on the enchanter.
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