I have no idea what I'm talking about. Start here:
https://forum.winehq.org/viewtopic.php?t=30705
As for the mouse issue, there is something about locking the FPS to 60. I eventually just accepted I had to play in windowed mode, and set the resolution to different values until I got something that worked for me. I have no idea how to actually fix it to play fullscreen.
Here is some of the research from the mouse troubleshooting I did:
https://www.project1999.com/forums/s...d.php?t=383287