I'm not totally familiar with the entire event either, but it may just be the mist because I just checked in north karana and found a rabid griffawn roaming, which is a mob associated with the plague. Also getting the "You feel dizzy." message every so often.
I seem to remember some kind of disease-based DOT effect is applied to you as soon as you zone into the karanas, too. Somebody other than me surely knows more.
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