Spreading them out has the advantage of making it far less likely you will lose exp when you drop the charm, it also is generally better for staggering a spawn so they reop at consistent rate and aswell as a consistent pattern you can more easily control. Clumping is faster but may have issues targeting stuff, and you may end up with a mob with like 50ish HP at the end and nothing to do with it and it will generally be harder to know when/which mobs root has broken.
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