You can max out all of your spellcasting skills, but you can only specialize one past 50. Specialization reduces the mana cost of spells, as opposed to reducing fizzles (which spellcasting skills do). "Specialize: SCHOOL" are a set of skills you learn automatically at level 20 (for INT casters) or 30 (for WIS casters); the first one you raise past 50 will be the only one you can continue raising past 50.
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