I'd always go alteration. You know it'll help you always, no matter what you're doing; raiding, grouping, especially soloing. Conjuration will sometimes help when you're fucked and have to mez everything ten times, but then you're probably fucked no matter what, and it's also just as likely that you'd have more mana left from your cheaper buffs than what you'll save from your cheaper mez. I'd say alteration is the best option in every case except the one where you go from full to zero mana solely on mezzing, and how often does that happen?
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