Only buff agi if you are regularly going high enough encumbrance or low enough health to drop agi below 75.
Str and ac should be enough, if you’re xping on particularly low cons you can probably skip ac.
They stack, you’ll want to play around to find what works best versus the particular mobs you are fighting.
I don’t think the gear will matter too much either way. Meleeing will lose you a lot of med and regen ticks, meaning you’ll want to use more of a burst dps approach compared to root rotting.
Check patch messages or do your own research to see if that nerf has been implemented yet.
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