(disclaimer: 20 year old recollection)
You can certainly tank post-50 but there has to be a good reason for it. You have no way to pick up aggro besides procs but with a healer and a Locustlure I'd definitely toss the epic in the offhand and go to town if needed.
As far as I understand nothing in the game sees through sneak (any class, not just rogues) but you have to be behind them. The rogue's hide/sneak combo is really like a supercharged invis & invis to undead. Definitely more things see through it but it's really solid. Also I believe if you invis a rogue it's essentially the same effect. Before level 60 I used to pull corpses quickly with a cloudy potion in hate...so long as I didn't run into one of those damn loathing liches. If playing a rogue again I'd fill a backpack with those or some ring of shadows.
Poison making is a money pit but can be dang fun on occasion. I'd train it up to a moderate level. Bored people occasionally duel and the rogue doesn't fare well...muscle lock poison at least lets you panic people for a bit before they beat ya.
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