About 80% of the population should be female anyway. We don't need as many laborers as we used to -- especially with appropriate technology. Females are more orderly and compliant. Men are much happier with a surplus of women and the kinds of men worth keeping around can generally handle more than one.
With enough transhumanism people could theoretically switch back and forthwith or change for the needs or their job or desires. Now it tends to be more of a one-way ticket where the best results come from those that decide as a child...far from an ideal situation.
And that's just the gender piece. The other huge area might would be mental health and cognitive abilities. Both can be greatly improved if your not all techno-phobic about this stuff.
Life greatly extended (and more youthful) and human potential can truly become unbound by some of natural barriers. It is the future as I see it.
Zuckerberg is already working on that thought reading machine of his. We are severely limited by language ATM.
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