Seriously check it out, go in game and test it put a spell on gem #1 and cast, hit a clicky, and #1 always refreshes instantly, whereas no other spell gem will refresh instantly upon casting that respective spell gem...I've read Loraen's guide and watched Tecmos Deception's vids as well as Loraen with his little gnome fighting bosses and the like. In his guide he mainly mentions regarding spell slots about having all the CC tools ready, which is helpful, however doesn't mention anything regarding advantageous use of the GCD reset in spell slot #1.
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