Yeah, north has a handful of stuff off the nameds that will sell for a few hundred plat, plus the adamantite club. 51-54 spells drop like candy, but aren't too valuable. West drops are basically the same as north except for the last boss who has a couple items worth a few k, but they aren't his common items.
South is where you can start to make real money. It's not like it used to be, but there are a several drops worth like 300-500pp, the fingerbone hoop and steel-hilted flint dagger (rare but big drops), and 55+ spells sometimes.
East is like... probably about the same overall farm loot quality as south, except that it's harder because you'll usually have to use a 51+ pet and the nameds are tougher (one is even 56, and therefore immune to stun and mez... and is a shadowknight to boot so he likes to dot the shit out of your pet, which can make charm breaks extra challenging).
You don't need help getting through doors in HS. There's keeping keys on corpses (and being OCD about not letting them rot or logging with one on you). There's the stalking probe trick. There's getting summoned to the other side of a locked door. For CRs, keep cheap charisma gear and stalking probes and peridots and foot+water and stuff like that in your bank. If you absolutely need to do it solo, you can get that stuff from the outpost bank to do a CR yourself.
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