Something about classic-specificity seems trivializing to me - as powerful as some spells like Torpor or Complete Healing are, they're still restricted to that class, and SoulFire is too bottlenecked and Reapers are too expensive. And despite the utility of Torpor, enchanters are far more powerful soloers. Which makes me want to change my answer: Puppet Strings, assuming you have no issues dropping the half a million on a pair. After that it's 80pp per click for sheer unadulterated game destruction.
Other than that, Red and White Dragon Tooth seem to have some seriously gamebreaking potential, assuming they haven't been nerfed. If you're willing to roll the dice you could theoretically powerlevel yourself from 1 to 50 in one playing session, assuming your pet doesn't die.
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