I expect for a twinked rogue they would be quite handy. Back on Live I could solo a fairly easy blue with a poison (like dogs in Sol B) and my gear was never that good. Most rogues never made it which I didn't understand...it's probably the most boring class of all time otherwise
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The materials are where the crafting game gets annoying. If I was rolling a rogue again at some point I'd prob hit up Najena and kill the ogres for Whore's Bane. Lethargic Bliss is Muscle Lock 2 and the skill to triv it is fairly low. A 50% slow is nothing to sneeze at and worth keeping for that special occasion.