AMD mobo's usually have an onboard video chip set. Mine does. The way you can tell is go into bios settings and examine the video settings which I think are in advanced settings. It will give you an option to enable/disable the onboard video. If onboard is off, I wouldn't even bother with it, just do the swap.
But anywawy, you just simply uninstall the drivers, power down, swap the card and power up. When you power up you can check bios settings and see if it's being recognized, optional. As windows starts, it'll recognize new hardware and give you a prompt. You have the disk with drivers, install it. When it starts, it'll be using generic drivers which is normal, as you removed the old drivers, and so you install the new drivers and control suite.
Standard procedure, we even did this in my A+ prep class in college. Even on current hardware, I put an Radeon in my ASUS system originally and then later swapped it out for a Geforce.
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