If you're tanking you should probably use a Lute anyway. More than doubling Rune song + HP Regen probably more important to a full group than your DPS output if you're the only one that can tank, and aggro won't be a problem regardless.
The only real 'reason' to use weapons 40+, realistically is to (1) proc weapon effects, (2) push mobs to prevent gate or CH, or (3) Mez/Melee mobs in dungeons that you don't have room to fear kite.
Someone might argue that fear kiting with epic MH + worn haste + chants/dots is more damage than drums of the beast MH....but I'd be surprised. Again, the 'reason' you melee is when your group doesn't need you to be enhancing your songs with an instrument effect.
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