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repeating the answer given by pharmaceutical lobbies eh ? r&d costs are overestimated and most of the time confidential, how convenient. Not even mentioning that in france at least, a good chunk of that r&d cost is financed by the government itself.. ¯\_(ツ)_/¯
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I mean I'm probably one of the last people who would defend the current state of the pharmaceutical industry; I think there need to be some serious changes in the industry and other industries related to IP. However to present a case where the supposed margin is 20000% and then only give evidence for 40% perfectly illustrates my point that the bulk of the cost is research, not production.
A book I like is
Against Intellectual Monopoly. There are some holes in their arguments for sure, but it presents an interesting case against strict IP laws.