Best group for what?
Until you define what you want to do this question is impossible.
If you want to kill big trophy stuff, any 2 classes with a level 60 torpor/epic shaman.
For raw leveling speed that's a toss up, but enchanters for charm dps are a prime choice as are necros as are shamans as are well geared monks. Cleric and ench with charmed pet are insanely powerful. For speed of leveling, I would vote a caster group that has a necro in it. (could be sham/ench or cleric/ench). For raw speed of leveling, bard + 2 others (preferably with aoe).
For doing trio in tricky places like kael arena? Make sure you have a monk to split stuff. Monk ench cleric works.
But yeah, until define what you want to do the question is impossible. No "best" trio will include rangers, paladins, sks, bards, druids ... etc, but each of these classes can fit very nicely into a good functional trio.
The undeniable "power" classes:
shaman
enchanter
necromancer
cleric
monk
Pick 3 and roll.
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