As a first character, most people will say that you should stick to a non-gear dependent class. Which does make sense, unless you are fortunate enough to meet & greet a bunch of others that unload a cache of items for you. At this point in the time line, the hybrid class penalties are gone & there are many players that are knowledgeable in helping you with any questions or difficulties you may have. You mention gnome hybrids which are not on this server (and never will be?) so that will lessen your choices more so which leaves you with Iksar or DE for SK and Dwarf or 1/2elf for Pally. There will be some that will tell you that High Elf is the better choice but in the end it's totally up to you in what you really want to log in and play.
Some people make a porting class as their first character to make some platinum & farm or buy items & twink out the more gear dependable classes but again, it's ultimately up to what you really want to play. It can be a long grind though the levels so pick what ever way you wish to play the game.
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