I had this problem, too. At first I suspected it was because I have separate user and admin accounts on my machine, but I'm beginning to think that Microsoft just screwed the pooch on file permissions.
To change the server login, I changed the original eqhost.txt to eqhost.txt.orig or something and opened notepad as an administrator. I then pasted the text to change the login server and saved the file as eqhost.txt.
To change the spells_us and other files, extract them to a directory on your desktop then move them over to the appropriate directories. Windows should prompt you for admin access before doing it, but it shouldn't deny you access afterwards.
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