Running mobs take reduced damage if they are chasing. I see two options to try against these mammoth calves.
Rooting them to the spot will improve your dps and allow you to meditate.
Alternatively you can try improving your dps by meleeing them (this will improve your Dots similar to rooting the mob but you can also swing your weapon). I suggest wearing strength, inner fire, an AC buff and maybe even fleeting fury.
The final option is to find something to XP on for another level or two. Spirit strike really eats away at things quickly!
Oh, bonus option. Run diagonally, even with sow you'll run faster. Once you've made some good distance sit down, meditate and then recast your dot just before it fades.
Final check: you did remember to train meditate, right?
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