It doesn't last long usually. My charm gear (have a pretty full set, minus a +15Cha crown -- Vermiculated/King Tranix Crown) left me around 150ish Charisma.
At that point it is still worthwhile. The thing most people don't realise, is that even though you spend alot of mana on it (200 at level 44-50) the damage per mana of the spell, if you consider it doing the damage to both your charmed pet / the mob its fighting, is much higher than our other options for damage. Even if it lasts 20 seconds that is still more efficient than 1 DoT.
Sometimes it'll last 5minutes and I'll be able to kill 3 mobs + my charmed mob in that time with just casting charm once (this is once you get Savage Spirit for haste). I like it because it is usually a fast kill, it is a wager because it can turn against you or the RNG can make it a complete waste of time, but when I play I afk during my med breaks and do other things IRL or troll the internet. So even if i have to gate out due to multiple charm breaks I don't really mind.
This is coming from someone who did level 37-50 almost exclusively in Kedge Keep.
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