At level 59 pox costs 20% of 2150 mana, and bane 22%. So after slow/root/epic/bane/pox you're down to 44% mana - Canni2 won't come close to regening it to 100% so you can JBbracer-nuke before the dots wear off. If you have trouble with hp falling too much/fast, just wait ~ 3 to 3.5 secs after each canni for that extra hp tick using Canni3.
|