I've gotten my iksar monk friendly to every NPC in Kaladim and Felwithe, and friendly with enough other factions in Faydwer that he can bank in every city on that continent. I just did this for fun. Sneak helps a lot; so does paying druids to wolf form you when possible (i.e. when outdoors). I would not recommend doing it for any reason other than it's something you have fun with, although with sneak you can very quickly get friendly enough in Kaladim to bank safely. Obviously, all of this is harder or easier depending on your race: a dark elf will find it a lot easier to raise faction than an iksar.
Here's a run-down of what I did with sneak and what you can do without sneak.
Kaladim: CB belt turn-ins. Can do this immediately if you get an invis in, then de-invis while sneaking behind Canloe Nusback. As you hand in belts, he does not turn around, and no one sees you. You get a ton of faction quickly this way and become friendly with the Kaladim guards, rogues, and merchants. If sneak is not an option, you'd first need to kill a ton of orcs/goblins/aviaks to get adequate faction with Storm Guard to do the quest. You can then get friendly with the cleric and paladin guild by doing the bone chip turn-in quest (again, invis behind the NPC, Gunlok Jure, then sneak and de-invis), and one of these quests also gets you friendly with the king, Kazon Stormhammer. Finally, there is a lone bard in Kaladim. You can get friendly with him by going to East Freeport and repeatedly handing in 2gp to Fabian while in wolf form. You need to do this a lot - I think I spent a couple hundred plat doing this. This also makes you friendly with Knights of Truth (paladin guild, I believe, with guards named Sir ___ patrolling North Freeport) and Guards of Qeynos.
Kelethin and Felwithe: Kill a lot of orcs and do the slaver keys quests with sneak. Eventually you'll be friendly with the guards of these cities. This will let you get around both cities reasonably safely if you know who to avoid. The bankers will still try to kill you. To get faction with the bankers, I did the Shark Meat quest and the Emerald Warriors' Items quest at the Kelethin warrior guild. Both sets of items can be farmed reasonably easily and both quests give you faction with Kelethin and Felwithe merchants, which also means the bankers. You can also, using sneak (or probably using wolf form), do the bone chips quest in Felwithe and the bat wings quest in Felwithe to get friendly with the rest of the NPCs in that city. I gave up on the rest of the Kelethin NPCs because factioning them was too much of a hassle, but I can get around the city fine.
Ak'Anon: Kill a lot of aqua goblins in Butcherblock and kobolds and minotaurs in Steamfont to get your Gem Choppers faction up (Ak'Anon guards). I found that the merchants of Ak'Anon, surprisingly enough, either started out friendly to my Iksar or were easy to get faction up by killing the above monsters (i.e. once I was OK with the guards, I was mostly OK with the merchants). You can do the Rusted Blackboxes quest in the warrior guild for some additional faction, but I didn't find that it gave much faction. I gave up on the various caster guilds in this city, though with some cleverness you could probably faction them up somewhat (don't know if it would be doable quickly, though).
Additionally, in Qeynos, if you kill a lot of gnolls, you can do the gnoll fang and moonstone quests in wolf form for a lot of faction throughout the city, as well as the bone chips quest outside of Qeynos, but you will still have trouble banking because of the caster GMs that patrol throughout South Qeynos and particularly around the bank. These three easily-spammable quests will raise faction with pretty much every faction in Qeynos other than the casters and evils. The caster guild faction is not so easy to raise in my experience, though doable if you really want to. On the other hand, I believe if you do not do faction work in Qeynos, the catacombs will be a viable place to sell and bank even if you are an Iksar.
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