Pick a pure caster, a healer, a tank and a melee dps.
1 of each... no more! Stick to those 4 until they're all at least into their 40s/50s.
That way you've got all bases covered... you don't need a wizard/necro/mage/enchanter. They all cross over anyway in their own ways, as do healers, tanks and melee dps
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