The answer is to minimize damage taken. Have bedlam in front of rune.
Root the mob you are fighting against. On charm breaks, aoe stun -> aoe mez -> recharm.
If a caster is targeting you with a spell, interrupt it.
Leave your top buff slot open for DoTs to cancel magic if fighting necro/druid mobs. Carry around 10 dose poison/disease cure potions if in an area with shaman/necro mobs.
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