Cleric/Healer UI and a screenshot please
 

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I just use the Vert Blue UI with classic spell icons, never cared for Luclin+ icons.

Bank 1:
Spell Macros
Jboots/instant click
Assist Key
Sit
Rez macro
Donal's macro

Bank 2:
Item spots tied to keys for bank 1
Other items with right click effects
Other macros indicating non-heal spells or other important messages.

Bank 3:
Targeting hotkeys for common tanks/pullers/enchanters

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Nope. Items need to be either equipped or in a bag slot.

It is an old screen shot from an explanation of how to hotkey a healing macro with an item click.

You can add any item to a hotbar and associate a key press to activate it rather than opening your inventory to right click it. Using the alternative keypress, you can set a single key to activate two actions at once, but not two items, i.e. Flying Kick hotkey and monk epic, heal macro and donal's bp, sense heading with movement keys.